Seretide 50mcg/500mcg Accuhaler (Salmeterol/Fluticasone)

Who might consider this inhaler?

• Adults with persistent asthma not well controlled on a lower inhaled steroid dose.
• People who benefit from a combined maintenance inhaler rather than separate steroid and LABA inhalers.
• Certain COPD patients who have frequent exacerbations and a clinician-directed need for an ICS plus LABA.

How it works

• Fluticasone propionate 500 mcg per dose reduces swelling and mucus in the airways.
• Salmeterol 50 mcg per dose relaxes airway muscles to improve airflow.
• This is a preventer inhaler. It does not give quick relief during a sudden breathing attack. Keep a rescue inhaler such as albuterol on hand for fast relief.

How to use the Accuhaler

• Open the device, slide the lever until it clicks to load one blistered dose.
• Breathe out gently away from the mouthpiece. Do not blow into the inhaler.
• Seal your lips around the mouthpiece and inhale quickly and deeply.
• Hold your breath for about 10 seconds if you can, then breathe out slowly.
• Rinse your mouth and spit after each dose to lower the chance of oral thrush.
  Most adults use one inhalation twice daily, about 12 hours apart, as prescribed.

Tips for better control

• Use it at the exact times each day. Consistency matters for symptom control.
• Track your symptom days, rescue inhaler use, and any triggers.
• If you often need your rescue inhaler or wake at night with symptoms, ask your clinician to review your plan.

Seretide 50mcg/500mcg Side Effects

Not everyone gets side effects, but common ones can include:

• Hoarseness, throat irritation, cough, or a yeast infection in the mouth.
• Headache, mild tremor, or a fast heartbeat.
• With long-term high-dose steroid use, eye pressure changes, cataracts, reduced bone density, and slower wound healing occur. Regular checkups help monitor these risks.
• In COPD, there is a known pneumonia risk with inhaled steroids. Know the signs and seek care if you develop a fever, a new cough with phlegm, or chest pain.

Safety and interactions

• Tell your prescriber about heart disease, high blood pressure, seizure disorders, osteoporosis, glaucoma, diabetes, thyroid problems, or past infections like tuberculosis.
• Some medicines can raise steroid levels or blunt the effect of salmeterol. Examples include potent CYP3A4 inhibitors such as ketoconazole or ritonavir, some macrolide antibiotics, and azole antifungals. Non-selective beta blockers may reduce the benefit. Ask your clinician or pharmacist to check interactions.
• Do not use with another LABA-containing inhaler.
• Pregnancy or breastfeeding requires an individual risk-benefit discussion.

Storage and handling

• Keep the inhaler closed and dry at room temperature. Moisture can clump the powder.
• Do not wash the device. Wipe the mouthpiece with a dry tissue if needed.
• Check the dose counter so you are never caught without medication.

What you get

• A sealed disk device with individually sealed blister doses. Many packs contain 60 doses, though labeling varies by market. Always check your specific pack.

Available strengths

• Purple Inhaler (Salmeterol/Fluticasone)
• Seroflo Multihaler 500
• Flohale Respules (Fluticasone Propionate)

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