Azee 1000mg (Azithromycin)

Overview

Azee 1000mg Tablet is a potent antibiotic manufactured by Cipla Ltd., containing the active ingredient Azithromycin. Belonging to the macrolide class of antibiotics, Azithromycin is renowned for its broad-spectrum activity against a variety of bacterial pathogens. Azee 1000mg is specifically formulated to treat a range of bacterial infections, offering an effective solution for patients requiring high-dose therapy.

Indications

Azee 1000mg Tablet is indicated for the treatment of various bacterial infections, including:

• Respiratory Tract Infections: Community-acquired pneumonia, bronchitis, tonsillitis, pharyngitis, and sinusitis.
• Ear Infections: Acute bacterial otitis media.
• Skin and Soft Tissue Infections: Cellulitis, impetigo, and other superficial skin infections.
• Sexually Transmitted Infections: Chlamydia, gonorrhea, and chancroid.
• Other Infections: Typhoid fever and pelvic inflammatory disease.

Its broad-spectrum activity makes it a versatile choice for treating infections caused by susceptible organisms.

Mechanism of Action

Azithromycin, the active ingredient in Azee 1000mg, exerts its antibacterial effect by binding to the 50S ribosomal subunit of susceptible bacteria. This binding inhibits bacterial protein synthesis, thereby preventing bacterial growth and replication. Unlike many other antibiotics, Azithromycin has a long half-life, allowing for once-daily dosing and shorter treatment durations.

Dosage and Administration

The recommended dosage of Azee 1000mg Tablet is typically a single 1000mg dose, often administered as a one-time treatment for certain infections. However, the exact dosage and duration depend on the specific infection being treated and the patient’s clinical condition. It is crucial to follow the prescribing healthcare provider’s instructions regarding dosage and duration.

Azee tablets should be swallowed whole with a glass of water. They can be taken with or without food, but it’s advisable to take them at the same time each day to maintain consistent blood levels. Patients should complete the full course of therapy, even if they feel better before finishing the medication, to prevent the development of antibiotic-resistant bacteria.

Side Effects

While Azee 1000mg Tablet is generally well-tolerated, some patients may experience side effects. Common side effects include:

• Nausea or vomiting
• Diarrhea
• Abdominal pain
• Headache

These side effects are typically mild and transient. However, if any of the following serious side effects occur, medical attention should be sought immediately:

• Severe allergic reactions (e.g., rash, itching/swelling, severe dizziness, trouble breathing)
• Persistent diarrhea, which may indicate a new infection
• Signs of liver problems (e.g., yellowing of the skin or eyes, dark urine, loss of appetite)
• Heart rhythm disturbances (e.g., fast or irregular heartbeat)

Patients should inform their healthcare provider if they have a history of liver disease, heart problems, or are taking other medications that may interact with azithromycin.

Precautions and Contraindications

Azee 1000mg Tablet should be used with caution in individuals with:

• Liver Disease: As azithromycin is metabolized in the liver, dose adjustments may be necessary.
• Heart Conditions: Particularly those with a history of QT prolongation or arrhythmias, due to the potential for azithromycin to affect heart rhythm.
• Kidney Impairment: In cases of severe kidney dysfunction, dose modifications may be required.

The use of Azee 1000mg Tablet is contraindicated in patients with a known allergy to azithromycin or other macrolide antibiotics.

Drug Interactions

Azithromycin may interact with other medications, potentially altering their effects or increasing the risk of adverse reactions. Notable interactions include:

• Antacids: May reduce the absorption of azithromycin; it’s advisable to take antacids at least 2 hours before or after azithromycin.
• Anticoagulants: Azithromycin may enhance the effects of blood thinners like warfarin, increasing the risk of bleeding.
• Other QT-Prolonging Drugs: Concurrent use with other medications that affect heart rhythm should be approached with caution.

Patients should provide their healthcare provider with a complete list of all medications they are taking to assess potential interactions.

Storage and Handling

Azee 1000mg Tablets should be stored at room temperature, away from moisture and heat. They should be kept out of reach of children and not used after the expiration date printed on the packaging.

Related Products

For patients requiring alternative formulations or dosages of Azithromycin, the following related products are available:

• Azee 250mg Tablet: A lower dosage option for less severe infections.
• Azee 500mg Tablet: Intermediate dosage for moderate infections.

Note

This product description is intended for informational purposes only and should not be used as a substitute for professional medical advice. Always consult with a healthcare provider before starting any new medication.