Indocap 75 mg Capsule SR

Indocap SR 75mg Capsule: Comprehensive Overview

Indocap SR 75 mg Capsule is a sustained-release formulation of Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID) commonly prescribed for the management of various inflammatory and painful conditions. This medication is designed to provide prolonged relief from pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gout.

Therapeutic Uses

Indocap SR 75 mg Capsule is indicated for the treatment of:

Osteoarthritis

A degenerative joint disease characterized by the breakdown of cartilage and underlying bone, leading to pain and stiffness.

Rheumatoid Arthritis

An autoimmune disorder that causes chronic inflammation of the joints, resulting in pain, swelling, and potential joint damage.

Ankylosing Spondylitis

A type of arthritis that primarily affects the spine, leading to inflammation and potential fusion of spinal vertebrae.

Acute Gout

A form of arthritis characterized by sudden, severe attacks of pain, redness, and swelling in the joints, often affecting the big toe.

The sustained-release formulation allows for extended therapeutic effects, reducing the frequency of dosing and improving patient compliance.

Mechanism of Action

Indomethacin, the active ingredient in Indocap SR, works by inhibiting the cyclooxygenase (COX) enzymes COX-1 and COX-2. These enzymes are involved in the synthesis of prostaglandins, which are chemicals in the body that promote inflammation, pain, and fever. By blocking these enzymes, Indocap SR reduces the production of prostaglandins, thereby alleviating pain and inflammation associated with various conditions.

Dosage and Administration

The recommended dosage of Indocap SR 75 mg Capsule should be determined by a healthcare provider based on the individual’s medical condition and response to treatment. Typically, the capsule should be swallowed whole with a glass of water, preferably with food to minimize gastrointestinal discomfort. It is important not to crush or chew the capsule to maintain the sustained-release mechanism.

Common Side Effects

While Indocap SR 75 mg Capsule is effective in managing pain and inflammation, it may cause side effects in some individuals. Common side effects include:

• Nausea
• Vomiting
• Stomach pain or discomfort
• Indigestion
• Headache
• Dizziness
• Constipation or diarrhea

These side effects are generally mild and may subside as the body adjusts to the medication. However, if any of these effects persist or worsen, it is advisable to consult a healthcare professional.

Serious Side Effects

Although rare, serious side effects may occur. Patients should seek immediate medical attention if they experience:

• Signs of gastrointestinal bleeding, such as black, tarry stools or vomit that looks like coffee grounds
• Unexplained weight gain or swelling
• Persistent abdominal pain
• Yellowing of the skin or eyes (jaundice)
• Severe headache or visual disturbances
• Skin rash or itching

These symptoms may indicate serious complications and require prompt medical evaluation.

Precautions and Contraindications

Before starting treatment with Indocap SR 75 mg Capsule, individuals should inform their healthcare provider of:

• Any known allergies to indomethacin or other NSAIDs
• History of gastrointestinal disorders, such as peptic ulcer disease or gastrointestinal bleeding
• Pre-existing kidney or liver conditions
• Cardiovascular issues, including hypertension or heart failure
• Asthma or other respiratory conditions
• Pregnancy or breastfeeding status

Indocap SR is not recommended during the third trimester of pregnancy and should be used with caution during the first and second trimesters. It is also contraindicated in breastfeeding mothers due to potential risks to the infant.

Drug Interactions

Indocap SR 75 mg Capsule may interact with other medications, potentially altering its effectiveness or increasing the risk of adverse effects. Patients should inform their healthcare provider of all medications they are taking, including over-the-counter drugs and herbal supplements. Particular caution is advised when combining Indocap SR with:

• Other NSAIDs or corticosteroids
• Anticoagulants (blood thinners)
• Antihypertensive agents
• Lithium
• Methotrexate

These interactions may necessitate dosage adjustments or close monitoring by a healthcare professional.

Storage Recommendations

Indocap SR 75 mg Capsule should be stored at room temperature, away from direct light and moisture. Keep the medication out of reach of children and dispose of any expired or unused capsules appropriately.